Product Description
|
Item
|
Value
|
| Molecular Formula |
C11H15N2O8P |
| Molecular Weight |
334.22 |
| Appearance |
Lyophilized white powder |
| Purity |
>=95% (HPLC) |
| Water contents |
< 8 % |
| Molecular extinction coefficient at 260 nm |
4200±200 L-mole-1-cm-1 |
| Recommended storage conditions |
below -20ºC in dry for long-term |
Basic Information
Chemical Name: β - Nicotinamide Mononucleotide, abbreviated as NMN. A purity of 99.5% indicates that the proportion of the NMN component in this product is very high. CAS Registry Number: 1094 - 61 - 7.
Physical Properties
Appearance: It generally appears as a white to light yellow powdery substance.
Solubility: It has relatively good solubility in water, forming a transparent solution. This enables it to be conveniently used for the preparation of various dosage forms, such as oral liquids and injections. It also has a certain degree of solubility in some organic solvents, but relatively weaker.
Melting Point: It is approximately between 160 - 162 °C. The determination of the melting point range is helpful for product quality control and identification.
Chemical Properties
Stability: It is relatively stable under normal temperature and dry conditions, but it is rather sensitive to environmental factors such as light, heat, and humidity. For example, in a high-temperature and humid environment, NMN may undergo decomposition reactions, which will affect its quality and efficacy.
Acid - base Reaction: The NMN molecule contains functional groups such as phosphate groups and amino groups, endowing it with certain acid - base properties. In acidic or alkaline environments, corresponding protonation or deprotonation reactions will occur.
Redox Properties: As an intermediate in the synthesis of NAD+, NMN participates in the intracellular redox metabolic processes. It can accept or provide electrons and plays a crucial role in cellular energy metabolism and biosynthesis reactions.
Quality Standards and Detection
Purity Detection: Besides the labeled 99.5% purity, precise analytical techniques such as High-Performance Liquid Chromatography (HPLC) are used to accurately measure the content of NMN to ensure that the product quality meets the standards. Meanwhile, other impurity components, such as unreacted raw materials and by-products, will also be detected.
Microbial Limit Detection: Microorganisms such as bacteria, molds, and yeasts are detected, and limits on their quantities are set. For example, the total number of bacteria is generally required to be controlled within a certain range to ensure the safety and stability of the product.
Heavy Metal Detection: The contents of heavy metals such as lead, mercury, and cadmium in the product are strictly detected to ensure that they meet the relevant standards and prevent harm to the human body caused by excessive heavy metal levels.
Functions and Applications
Healthcare Functions:
Cellular Energy Metabolism: As a precursor substance of NAD+, NMN can increase the intracellular NAD+ level. NAD+plays a key role in energy metabolism pathways in cells, such as mitochondrial respiration and glycolysis, which helps to enhance cellular energy production and improve physical functions.
Anti - aging Effect: Research has shown that the level of NAD+ in the human body decreases with age. Supplementing with NMN can increase the content of NAD+, activate proteins related to longevity (such as the Sirtuins family proteins), and play a role in gene repair, cell cycle regulation, and other aspects, thereby delaying the aging process to a certain extent.
Application Fields:
Health Product Industry: Products with 99.5% purity of NMN are mainly applied in the high-end health product market. They are sold in dosage forms such as capsules, tablets, and oral liquids for consumers to take on a daily basis to improve physical functions, enhance immunity, and relieve fatigue.
Medical Research Field: As a potential drug research object, it is used to study the treatment of diseases related to aging, such as neurodegenerative diseases (Alzheimer's disease, Parkinson's disease), cardiovascular diseases, etc. In clinical trials, the treatment mechanisms and effects of these diseases are explored.
Dosage and Usage Recommendations
Dosage Range: Generally speaking, the dosage of NMN for healthcare purposes varies from person to person. Usually, it is around 100 - 500 mg per day. However, the specific dosage should be adjusted according to factors such as an individual's age, health status, and physiological needs.
Usage Method: It can be taken orally and absorbed into the bloodstream through the gastrointestinal tract. To improve the absorption efficiency, some products will adopt special formulation technologies, such as liposome encapsulation. Meanwhile, it is best to follow the product instructions or the advice of professionals when using it.
Storage and Transportation
Storage Conditions: It should be sealed and stored in a cool, dry, and dark environment. For example, it can be stored in a dry cabinet or a specialized medicine storage box, and the temperature is preferably controlled between 2 - 8 °C.
Transportation Requirements: During transportation, attention should be paid to avoiding high temperatures, sunlight, and rain. Appropriate packaging materials should be used, such as well-sealed plastic bottles or aluminum foil bags, and then put into outer packaging such as carton boxes to ensure the quality stability of the product during transportation.
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